The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 26, 2017

Filed:

Oct. 31, 2006
Applicants:

Austin Gurney, San Francisco, CA (US);

John Lewicki, Los Gatos, CA (US);

Sanjeev Satyal, San Carlos, CA (US);

Timothy Hoey, Hillsborough, CA (US);

Inventors:

Austin Gurney, San Francisco, CA (US);

John Lewicki, Los Gatos, CA (US);

Sanjeev Satyal, San Carlos, CA (US);

Timothy Hoey, Hillsborough, CA (US);

Assignee:

ONCOMED PHARMACEUTICALS, INC., Redwood City, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 16/00 (2006.01); C07K 16/30 (2006.01); A61K 45/06 (2006.01); C07K 16/28 (2006.01); C07K 16/46 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
C07K 16/30 (2013.01); A61K 45/06 (2013.01); C07K 16/2896 (2013.01); C07K 16/468 (2013.01); A61K 2039/505 (2013.01); C07K 2317/73 (2013.01); C07K 2317/732 (2013.01); C07K 2317/734 (2013.01); C07K 2317/76 (2013.01);
Abstract

An isolated antibody that specifically binds to an extracellular domain of two or more human FZD receptors and inhibits growth of tumor cells is described. Also described is a method of treating cancer comprising administering an antibody of the present disclosure in an amount effective to inhibit tumor cell growth.


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