The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 26, 2017
Filed:
Apr. 30, 2015
Deutsches Krebsforschungszentrum Stiftung Des Oeffentlichen Rechts, Heidelberg, DE;
Universitaetsklinikum Heidelberg, Heidelberg, DE;
Ana Martin-Villalba, Heidelberg, DE;
Susanne Kleber, Heidelberg, DE;
Benedikt Wiestler, Schriesheim, DE;
Peter G. Krammer, Heidelberg, DE;
Christel Herold-Mende, Bammental, DE;
Ignacio Sancho-Martinez, Heidelberg, DE;
DEUTSCHES KREBSFORSCHUNGSZENTRUM STIFTUNG DES OEFFENTLICHEN RECHTS, Heidelberg, DE;
UNIVERSITAETSKLINIKUM HEIDELBERG, Heidelberg, DE;
Abstract
The present invention relates to methods for treating an individual with high grade glioblastoma multiforme by preventing or disrupting the binding of CD95 to its ligand, CD95L, in vivo, whereupon that neutralization of CD95 activity reduces undesirable glial cell migration and invasion into body tissue.