The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 26, 2017
Filed:
May. 26, 2016
Applicants:
Jigneshkumar Jasubhai Patel, Vallabh Vidyanagar, IN;
Raja Jeyakumar John Muthiah, Vadodara, IN;
Inventors:
Jigneshkumar Jasubhai Patel, Vallabh Vidyanagar, IN;
Raja Jeyakumar John Muthiah, Vadodara, IN;
Assignee:
Navinta, LLC, Ewing, NJ (US);
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07F 9/6558 (2006.01); A61K 31/675 (2006.01); C07C 211/35 (2006.01);
U.S. Cl.
CPC ...
C07F 9/65583 (2013.01); A61K 31/675 (2013.01); C07C 211/35 (2013.01); C07F 9/65586 (2013.01); C07C 2601/14 (2017.05);
Abstract
The present invention provides dicyclohexylamine salt of fosaprepitant (fosaprepitant DCHA), a process for preparing fosaprepitant DCHA, and a use of fosaprepitant DCHA in the preparation of pharmaceutically acceptable fosaprepitant dimeglumine with high purity. Fosaprepitant dimeglumine is prepared by treating fosaprepitant DCHA with an acid to form fosaprepitant, followed by adding N-methyl-D-glucamine to fosaprepitant.