The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 26, 2017

Filed:

May. 15, 2017
Applicant:

Redx Pharma Plc, Greater Manchester, GB;

Inventors:

Sandro Boland, Diepenbeek, BE;

Arnaud Bourin, Diepenbeek, BE;

Olivier Defert, Diepenbeek, BE;

Dirk Leysen, Diepenbeek, BE;

Assignee:

Redx Pharma PLC, Greater Manchester, GB;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 273/01 (2006.01); C07D 405/12 (2006.01); A61K 31/35 (2006.01); A61K 31/435 (2006.01); A61K 31/4355 (2006.01); A61K 45/06 (2006.01); A61K 31/33 (2006.01);
U.S. Cl.
CPC ...
C07D 405/12 (2013.01); A61K 31/33 (2013.01); A61K 31/435 (2013.01); A61K 31/4355 (2013.01); A61K 45/06 (2013.01); C07D 273/01 (2013.01);
Abstract

The present invention relates to new kinase inhibitors, more specifically ROCK inhibitors, compositions, in particular pharmaceuticals, comprising such inhibitors, and to uses of such inhibitors in the treatment and prophylaxis of disease. In particular, the present invention relates to new ROCK inhibitors, compositions, in particular pharmaceuticals, comprising such inhibitors, and to uses of such inhibitors in the treatment and prophylaxis of disease. In addition, the invention relates to methods of treatment and use of said compounds in the manufacture of a medicament for the application to a number of therapeutic indications including Respiratory and Gastro-Intestinal diseases.


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