The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 26, 2017
Filed:
Nov. 07, 2014
Applicant:
Virginia Commonwealth University, Richmond, VA (US);
Inventors:
Umesh R. Desai, Glen Allen, VA (US);
Rajesh Karuturi, Richmond, VA (US);
Bhaumik B. Patel, Glen Allen, VA (US);
Nirmita J. Patel, Glen Allen, VA (US);
Assignee:
VIRGINIA COMMONWEALTH UNIVERSITY, Richmond, VA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 311/30 (2006.01); C07D 405/12 (2006.01); C07D 407/12 (2006.01);
U.S. Cl.
CPC ...
C07D 311/30 (2013.01); C07D 405/12 (2013.01); C07D 407/12 (2013.01);
Abstract
Sulfated and unsulfated flavonoid oligomers as inhibitors of cancer stem cells (CSCs) are provided. In particular, sulfated flavonoid dimers are shown to selectively inhibit CSCs growth and self-renewal both in vitro and in vivo.