The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 26, 2017
Filed:
Sep. 10, 2015
Applicant:
Sunovion Pharmaceuticals Inc., Marlborough, MA (US);
Inventors:
Liming Shao, Lincoln, MA (US);
Fengjiang Wang, Northborough, MA (US);
Scott C. Malcolm, Southborough, MA (US);
Michael C. Hewitt, Somerville, MA (US);
Assignee:
Sunovion Pharmaceuticals Inc., Marlborough, MA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/4035 (2006.01); C07D 209/08 (2006.01); C07D 209/52 (2006.01); C07D 209/44 (2006.01);
U.S. Cl.
CPC ...
C07D 209/44 (2013.01); A61K 31/4035 (2013.01); C07D 209/08 (2013.01); C07D 209/52 (2013.01);
Abstract
Provided herein are bicyclic compounds and methods of synthesis thereof. The compounds provided herein are useful for the treatment, prevention, and/or management of various neurological disorders. Compounds provided herein inhibit reuptake of endogenous monoamines, such as dopamine, serotonin and norepinephrine (e.g., from the synaptic cleft) and modulate one or more monoamine transporter. Pharmaceutical formulations containing the compounds are also provided.