The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 26, 2017
Filed:
Feb. 04, 2016
Applicant:
Molecular Partners Ag, Schlieren, CH;
Inventors:
Hans Kaspar Binz, Birmensdorf, CH;
Patrik Forrer, Dietikon, CH;
Michael Tobias Stumpp, Geroldswil, CH;
Assignee:
Molecular Partners AG, Schlieren, CH;
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 38/16 (2006.01); A61K 47/48 (2006.01); C07K 14/515 (2006.01); A61K 38/17 (2006.01); C07K 14/47 (2006.01); C07K 17/08 (2006.01); C07K 14/00 (2006.01); C07K 19/00 (2006.01); A61K 38/00 (2006.01);
U.S. Cl.
CPC ...
A61K 38/1709 (2013.01); A61K 38/16 (2013.01); A61K 47/48215 (2013.01); C07K 14/00 (2013.01); C07K 14/47 (2013.01); C07K 17/08 (2013.01); C07K 19/00 (2013.01); A61K 38/00 (2013.01); C07K 2319/74 (2013.01);
Abstract
The present invention relates to binding proteins specific for VEGF-A, in particular to recombinant binding proteins comprising a polyethylene glycol moiety and a binding domain, which inhibits VEGF-Axxx binding to VEGFR-2. Examples of such recombinant binding proteins are proteins which comprise an ankyrin repeat domain with the desired binding specificity, and a polyethylene glycol moiety. The binding proteins are useful in the treatment of cancer and other pathological conditions, e.g. eye diseases such as age-related macular degeneration.