The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 26, 2017

Filed:

Mar. 15, 2017
Applicant:

Roche Palo Alto Llc, South San Francisco, CA (US);

Inventors:

Li Chen, Shanghai, CN;

Michael Patrick Dillon, San Francisco, CA (US);

Lichun Feng, Shanghai, CN;

Ronald Charles Hawley, Mountain View, CA (US);

Minmin Yang, Shanghai, CN;

Assignee:

Roche Palo Alto LLC, Palo Alto, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A01N 61/00 (2006.01); A61K 31/00 (2006.01); A61K 31/5377 (2006.01); A61K 31/426 (2006.01); A61K 31/428 (2006.01); A61K 31/421 (2006.01); A61K 31/42 (2006.01); A61K 31/425 (2006.01); A61K 31/501 (2006.01);
U.S. Cl.
CPC ...
A61K 31/5377 (2013.01); A61K 31/42 (2013.01); A61K 31/421 (2013.01); A61K 31/425 (2013.01); A61K 31/426 (2013.01); A61K 31/428 (2013.01); A61K 31/501 (2013.01);
Abstract

A method for treating diseases mediated by a P2Xand/or a P2Xreceptor with compounds of the formula I: or a pharmaceutically acceptable salt thereof, wherein, Ris an optionally substituted thiazole, oxazole, isothiazole or isoxazole and X, R, R, R, R, R, Rand Rare as defined herein.


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