The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 26, 2017

Filed:

Jan. 25, 2013
Applicants:

President and Fellows of Harvard College, Cambridge, MA (US);

Health Research, Inc., Menands, NY (US);

Inventors:

Daniel J. Finley, Jamaica Plain, MA (US);

Dilip Nag, Delmar, NY (US);

Laura D. Kramer, Albany, NY (US);

Assignees:

President and Fellows of Harvard College, Cambridge, MA (US);

Health Research, Inc., Menands, NY (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 31/5377 (2006.01); A61K 31/4025 (2006.01); A61K 31/402 (2006.01); A61K 31/454 (2006.01); A61K 31/496 (2006.01); A61K 31/4545 (2006.01); A61K 31/506 (2006.01); A61K 31/40 (2006.01); A61K 31/4178 (2006.01); A61K 31/4192 (2006.01); A61K 31/437 (2006.01); A61K 31/4985 (2006.01);
U.S. Cl.
CPC ...
A61K 31/5377 (2013.01); A61K 31/40 (2013.01); A61K 31/402 (2013.01); A61K 31/4025 (2013.01); A61K 31/4178 (2013.01); A61K 31/4192 (2013.01); A61K 31/437 (2013.01); A61K 31/454 (2013.01); A61K 31/4545 (2013.01); A61K 31/496 (2013.01); A61K 31/4985 (2013.01); A61K 31/506 (2013.01);
Abstract

Disclosed herein are methods of treating or preventing a viral infection resulting from infection by a flavivirus, comprising administering to a subject a small molecule inhibitor of USP14, represented by Formula (I) or a pharmaceutically acceptable salt, solvate, hydrate, prodrug, chemically-protected form, enantiomer or stereoisomer thereof, and pharmaceutical compositions comprising an effective amount of a compound of Formula (I) for use in the method.


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