The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 26, 2017
Filed:
Mar. 10, 2017
Buck Institute for Research on Aging, Novato, CA (US);
Unity Biotechnology, Inc., Brisbane, CA (US);
Mayo Foundation for Medical Education and Research, Rochester, MN (US);
The John Hopkins University, Baltimore, MD (US);
Remi-Martin Laberge, San Francisco, CA (US);
Judith Campisi, Berkeley, CA (US);
Albert Davalos, San Rafael, CA (US);
Marco Demaria, Groningen, NL;
Nathaniel David, San Francisco, CA (US);
Alain Philippe Vasserot, Carlsbad, CA (US);
James L. Kirkland, Rochester, MN (US);
Tamar Tchkonia, Rochester, MN (US);
Yi Zhu, Rochester, MN (US);
Jennifer Elisseeff, Baltimore, MD (US);
Chaekyu Kim, Pikesville, MD (US);
Okhee Jeon, Baltimore, MD (US);
Unity Biotechnology, Inc., San Francisco, CA (US);
Buck Institute for Research on Aging, Novato, CA (US);
Mayo Foundation for Medical Education and Research, Rochester, MN (US);
The John Hopkins University, Baltimore, MD (US);
Abstract
Methods are provided herein for selectively killing senescent cells and for treating senescence-associated diseases and disorders by administering a senolytic agent. Senescence-associated diseases and disorders treatable by the methods using the senolytic agents described herein include cardiovascular diseases and disorders associated with or caused by arteriosclerosis, such as atherosclerosis; idiopathic pulmonary fibrosis; chronic obstructive pulmonary disease; osteoarthritis; senescence-associated ophthalmic diseases and disorders; and senescence-associated dermatological diseases and disorders.