The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 19, 2017

Filed:

Jun. 22, 2015
Applicant:

International Business Machines Corporation, Armonk, NY (US);

Inventor:

Ajay K. Royyuru, Congers, NY (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
G01N 27/327 (2006.01); G01N 27/447 (2006.01); C12Q 1/68 (2006.01); B01L 3/00 (2006.01); G01N 33/487 (2006.01);
U.S. Cl.
CPC ...
G01N 27/44704 (2013.01); B01L 3/502761 (2013.01); C12Q 1/6869 (2013.01); G01N 27/447 (2013.01); G01N 27/44791 (2013.01); G01N 33/48721 (2013.01); B01L 2200/0663 (2013.01); B01L 2400/0421 (2013.01);
Abstract

A mechanism is provided for presenting single strands of a double strand molecule to a membrane. The double strand molecule is driven to a first side of the membrane by an electric field. The membrane has a first and second nanopore spaced apart by a nanopore separation distance. The first strand of the double strand molecule is captured in the first nanopore when driven to the first side of the membrane. The second strand is captured in the second nanopore by having the nanopore separation distance between the first nanopore and the second nanopore corresponding to a strand separation distance between the first and second strands, and/or by having captured the first strand to limit diffusion of the second strand. The first and second strands respectively in the first and second nanopores are individually stretched, by the first and second strands recombining on the second side of the membrane.


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