The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 19, 2017
Filed:
Feb. 21, 2014
Applicant:
Taiho Pharmaceutical Co., Ltd., Tokyo, JP;
Inventors:
Takao Uno, Tsukuba, JP;
Tadashi Shimamura, Tsukuba, JP;
Assignee:
Taiho Pharmaceutical Co., Ltd., Tokyo, JP;
Primary Examiner:
Int. Cl.
CPC ...
C07D 487/14 (2006.01); C07F 7/18 (2006.01); C07D 471/14 (2006.01); C07D 487/04 (2006.01);
U.S. Cl.
CPC ...
C07D 487/14 (2013.01); C07D 471/14 (2013.01); C07D 487/04 (2013.01); C07F 7/1852 (2013.01);
Abstract
A method for producing a pyrrolopyrimidine ring-containing tricyclic compound represented by Formula (1) or a salt thereof. The method comprising the steps of: (I) reacting an organoborane reagent with a compound represented by Formula (2) or a salt thereof, and (II) performing an intramolecular cyclization reaction of the reaction product of step (I) in the presence of a zerovalent palladium catalyst and an alkali metal hydroxide.