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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 9845321 B1

PDFFull Text
Date of Patent:
Dec. 19, 2017

Filed:

Jan. 08, 2016

1,3-dihydro-2h-benzimidazol-2-one derivatives substituted with heterocycles as respiratory syncytial virus antiviral agents

Applicant:

Janssen Sciences Ireland Uc, Little Island, County Cork, IE;

Inventors:

Abdellah Tahri, Anderlecht, BE;

Tim Hugo Maria Jonckers, Heist-op-den-Berg, BE;

Pierre Jean-Marie Bernard Raboisson, Rosieres, BE;

Sandrine Marie Helene Vendeville, Woluwe-Saint-Pierre, BE;

Lili Hu, Mechelen, BE;

Samuel Dominique Demin, Antwerp, BE;

Ludwig Paul Cooymans, Beerse, BE;

Assignee:

Janssen Sciences Ireland UC, Co Cork, IE;

Attorney:
Primary Examiner:

Nizal Chandrakumar

Int. Cl.
CPC ...
C07D 471/02 (2006.01); C07D 471/04 (2006.01); C07D 403/14 (2006.01); C07D 417/14 (2006.01); C07D 519/00 (2006.01);
U.S. Cl.
CPC ...
C07D 471/04 (2013.01); C07D 403/14 (2013.01); C07D 417/14 (2013.01); C07D 519/00 (2013.01);
Abstract

The present invention is concerned with novel 1,3-dihydro-2H-benzimidazol-2-one derivatives substituted with heterocycles having formula (I) stereoisomeric forms thereof, and the pharmaceutically acceptable addition salts, and the solvates thereof,wherein R, R, Z and Het have the meaning defined in the claims. The compounds according to the present invention are useful as inhibitors on the replication of the respiratory syncytial virus (RSV). The invention further concerns the preparation of such novel compounds, compositions comprising these compounds, and the compounds for use in the treatment of respiratory syncytial virus infection.

Find Patent Forward Citations

Tahri, Abdellah. (2017). 1,3-dihydro-2h-benzimidazol-2-one derivatives substituted with heterocycles as respiratory syncytial virus antiviral agents (U.S. Patent No. 9845321). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/9845321

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