The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 19, 2017

Filed:

Jan. 13, 2012
Applicants:

Jeffrey T. Borenstein, Newton, MA (US);

Joseph L. Charest, Cambridge, MA (US);

Joseph Cuiffi, Albuquerque, NM (US);

Alla Epshteyn, Brookline, MA (US);

Angela B. Holton, Tampa, FL (US);

James Ching-ming Hsiao, Watertown, MA (US);

Inventors:

Jeffrey T. Borenstein, Newton, MA (US);

Joseph L. Charest, Cambridge, MA (US);

Joseph Cuiffi, Albuquerque, NM (US);

Alla Epshteyn, Brookline, MA (US);

Angela B. Holton, Tampa, FL (US);

James Ching-Ming Hsiao, Watertown, MA (US);

Assignee:
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
B01L 3/00 (2006.01); C12M 1/12 (2006.01); G02B 21/33 (2006.01);
U.S. Cl.
CPC ...
B01L 3/502707 (2013.01); G02B 21/33 (2013.01); B01L 2200/0689 (2013.01); B01L 2300/0816 (2013.01); B01L 2300/0887 (2013.01);
Abstract

A microfluidic device is provided. The microfluidic device includes a first transparent, solid support layer. A first polymeric layer defining at least one chamber is attached to the first transparent, solid support layer. A semi-permeable membrane is attached to the first polymeric layer. A second polymeric layer is attached to the opposite side of the semi-permeable membrane from the first polymeric layer. The second polymeric layer has a thickness of less than 300 microns and defines at least one chamber positioned to overlap with at least one chamber in the first polymeric layer. A first manifold structure is attached to an input end of at least one chamber and a second manifold structure is attached to an output end of at least one chamber.


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