The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 19, 2017

Filed:

Sep. 11, 2013
Applicant:

Ajou University Industry-academic Cooperation Foundation, Suwon-si, Gyeonggi-do, KR;

Inventors:

Ki Dong Park, Seoul, KR;

Jin Woo Bae, Suwon-si, KR;

Kyung Min Park, Anyang-si, KR;

Eugene Lih, Seoul, KR;

Bae Young Kim, Gwangju, KR;

Yunki Lee, Seongnam-si, KR;

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C12N 9/00 (2006.01); A61L 27/52 (2006.01);
U.S. Cl.
CPC ...
A61L 27/52 (2013.01); A61L 2400/06 (2013.01);
Abstract

The present invention relates to a method for preparing a hydrogel, including the steps of: preparing an enzyme-immobilized support; making contacting with a polymer having a phenol or aniline functional group at a side change and the support in the presence of hydrogen peroxide to cross-link the same; and obtaining a hydrogel by separating the enzyme-immobilized support. According to the present invention, a hydrogel is formed by cross-linking a polymer having a phenol or aniline functional group at a side chain through an enzyme-immobilized support, and thus a hydrogel containing no enzymes is obtained. Therefore, the biomedical application range of a hydrogel can be expanded since it is possible to overcome an in vivo safety problem such as immune reaction caused by an enzyme.


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