The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 19, 2017

Filed:

May. 02, 2008
Applicants:

Ahuva Nissim, London, GB;

Yuti Chernajovsky, London, GB;

Bjarne Faurholm, Cape Town, ZA;

David Perrett, London, GB;

Paul Winyard, Exeter, GB;

Christopher Hughes, London, GB;

Stephen Mather, London, GB;

Francesco Dell'accio, London, GB;

Inventors:

Ahuva Nissim, London, GB;

Yuti Chernajovsky, London, GB;

Bjarne Faurholm, Cape Town, ZA;

David Perrett, London, GB;

Paul Winyard, Exeter, GB;

Christopher Hughes, London, GB;

Stephen Mather, London, GB;

Francesco Dell'Accio, London, GB;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 47/48 (2006.01); A61K 51/10 (2006.01); C07K 16/18 (2006.01);
U.S. Cl.
CPC ...
A61K 47/48538 (2013.01); A61K 47/48415 (2013.01); A61K 47/48423 (2013.01); A61K 47/48438 (2013.01); A61K 51/1096 (2013.01); C07K 16/18 (2013.01); C07K 2317/55 (2013.01); C07K 2317/565 (2013.01); C07K 2317/569 (2013.01); C07K 2317/622 (2013.01); C07K 2317/76 (2013.01);
Abstract

The present invention provides a composition comprising an antibody or fragment thereof against oxidized Collagen II (CII) in which the antibody or fragment thereof is conjugated to a pharmaceutically active moiety. The invention also provides a composition comprising an antibody or fragment thereof against oxidized Collagen II (Gil) and a detectable label. The invention further provides the use of such compositions in medicine, in particular for the treatment of an arthropathy, and in methods of diagnosis.


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