The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 19, 2017

Filed:

Oct. 07, 2015
Applicant:

St. Jude Children's Research Hospital, Memphis, TN (US);

Inventors:

Elaine Tuomanen, Brownsville, TN (US);

Elizabeth R. Mann, Germantown, TN (US);

Assignee:
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 39/02 (2006.01); A61K 39/09 (2006.01); C07K 14/315 (2006.01); C07K 14/47 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
A61K 39/092 (2013.01); C07K 14/3156 (2013.01); C07K 14/47 (2013.01); A61K 2039/543 (2013.01); A61K 2039/545 (2013.01); A61K 2039/55505 (2013.01); A61K 2039/55544 (2013.01); A61K 2039/55583 (2013.01); A61K 2039/575 (2013.01); A61K 2039/6068 (2013.01); A61K 2039/645 (2013.01); C07K 2319/00 (2013.01); C07K 2319/40 (2013.01);
Abstract

Compositions and methods are provided for the prevention and treatment of bacterial infections, including pneumococcal infections. Compositions provided herein comprise a variety of immunogenic fusion proteins, wherein at least one polypeptide component of a given fusion protein comprises a CbpA polypeptide and/or a cytolysoid polypeptide, or an active variant or fragment thereof. Methods are provided for the prevention and treatment of bacterial infections, including pneumococcal infections by employing the various immunogenic fusion proteins having at least one polypeptide component comprising a CbpA polypeptide and/or a cytolysoid polypeptide, or an active variant or fragment thereof.


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