The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 12, 2017
Filed:
Feb. 24, 2016
Applicant:
California Institute of Technology, Pasadena, CA (US);
Inventors:
Assignee:
CALIFORNIA INSTITUTE OF TECHNOLOGY, Pasadena, CA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A01N 63/00 (2006.01); C12N 15/86 (2006.01); A61K 31/70 (2006.01); A61K 38/17 (2006.01); A61K 38/19 (2006.01); A61K 38/20 (2006.01); C07K 14/005 (2006.01); A61K 35/76 (2015.01); A61K 39/21 (2006.01); C12N 7/00 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
C12N 15/86 (2013.01); A61K 31/70 (2013.01); A61K 35/76 (2013.01); A61K 38/177 (2013.01); A61K 38/178 (2013.01); A61K 38/1774 (2013.01); A61K 38/1793 (2013.01); A61K 38/191 (2013.01); A61K 38/193 (2013.01); A61K 38/20 (2013.01); A61K 38/204 (2013.01); A61K 38/2013 (2013.01); A61K 38/2026 (2013.01); A61K 38/2046 (2013.01); A61K 38/2086 (2013.01); A61K 39/21 (2013.01); C07K 14/005 (2013.01); C12N 7/00 (2013.01); A61K 2039/5256 (2013.01); C12N 2740/13043 (2013.01); C12N 2740/13045 (2013.01); C12N 2740/15041 (2013.01); C12N 2740/15043 (2013.01); C12N 2740/15045 (2013.01); C12N 2770/36122 (2013.01); C12N 2770/36134 (2013.01); C12N 2810/609 (2013.01); C12N 2810/855 (2013.01);
Abstract
Methods and compositions are provided for delivery of a polynucleotide encoding a gene of interest, typically an antigen, to a dendritic cell (DC). The virus envelope comprises a DC-SIGN specific targeting molecule. The methods and related compositions can be used to treat patients suffering from a wide range of conditions, including infection, such as HIV/AIDS, and various types of cancers.