The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 12, 2017
Filed:
Jul. 22, 2014
Applicant:
The Children's Hospital of Philadelphia, Philadelphia, PA (US);
Inventors:
Katherine High, Merion, PA (US);
Mustafa Yazicioglu, Philadelphia, PA (US);
Xavier Anguela, Philadelphia, PA (US);
Assignee:
The Children's Hospital of Philadelphia, Philadelphia, PA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 15/86 (2006.01); C07K 14/005 (2006.01); C12N 9/64 (2006.01); A61K 48/00 (2006.01); A61K 38/00 (2006.01);
U.S. Cl.
CPC ...
C12N 15/86 (2013.01); C07K 14/005 (2013.01); C12N 9/6408 (2013.01); C12Y 304/21022 (2013.01); A61K 38/00 (2013.01); A61K 48/0058 (2013.01); C12N 2750/14122 (2013.01); C12N 2750/14143 (2013.01); C12N 2830/008 (2013.01);
Abstract
The invention relates to adeno-associated virus (AAV) serotype AAV-Rh74 and related AAV vectors, and AAV-Rh74 and related AAV vector mediated gene transfer methods and uses. In particular, AAV-Rh74 and related AAV vectors target polynucleotides to cells, tissues or organs for expression (transcription) of genes encoding therapeutic proteins and peptides, and polynucleotides that function as or are transcribed into inhibitory nucleic acid sequences.