The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 12, 2017
Filed:
Oct. 05, 2012
Applicant:
Dana-farber Cancer Institute, Inc., Boston, MA (US);
Inventors:
Margaret A. Shipp, Wellesley, MA (US);
Qingsheng Yan, Wayland, MA (US);
Assignee:
Dana-Farber Cancer Institute, Inc., Boston, MA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 15/113 (2010.01); C12N 15/85 (2006.01); C12Q 1/68 (2006.01); G01N 33/574 (2006.01); C07K 16/40 (2006.01); C12N 9/10 (2006.01); C12N 9/00 (2006.01); C12Q 1/25 (2006.01); C12Q 1/48 (2006.01); G01N 33/573 (2006.01);
U.S. Cl.
CPC ...
C12N 15/1137 (2013.01); C07K 16/40 (2013.01); C12N 9/1077 (2013.01); C12N 9/93 (2013.01); C12N 15/8509 (2013.01); C12Q 1/25 (2013.01); C12Q 1/48 (2013.01); C12Q 1/6886 (2013.01); C12Y 603/02019 (2013.01); G01N 33/573 (2013.01); G01N 33/57484 (2013.01); C12N 2015/859 (2013.01); C12N 2310/11 (2013.01); C12N 2310/14 (2013.01); C12N 2310/16 (2013.01); C12N 2320/30 (2013.01); C12N 2320/31 (2013.01); C12Q 2600/158 (2013.01); C12Y 204/0203 (2013.01); C12Y 603/02 (2013.01); G01N 2333/9015 (2013.01); G01N 2333/91142 (2013.01); G01N 2500/10 (2013.01); G01N 2800/52 (2013.01);
Abstract
The invention provides methods and compositions for enhancing the efficacy of cancer therapies through modulation of BAL1 and/or BBAP. Also provided are methods for predicting the efficacy of cancer therapies or treating cancer in a subject through modulation of BAL1 and/or BBAP. Further provided are methods for identifying compounds that are capable of modulating BAL1-BBAP complexes.