The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 12, 2017
Filed:
Jun. 16, 2015
Applicants:
Nippon Shinyaku Co., Ltd., Kyoto-shi, Kyoto, JP;
National Center of Neurology and Psychiatry, Tokyo, JP;
Inventors:
Naoki Watanabe, Ibaraki, JP;
Yuuichirou Tone, Ibaraki, JP;
Shin'ichi Takeda, Tokyo, JP;
Tetsuya Nagata, Tokyo, JP;
Assignees:
NIPPON SHINYAKU CO., LTD., Kyoto-shi, Kyoto, JP;
NATIONAL CENTER OF NEUROLOGY AND PSYCHIATRY, Kodaira-shi, Tokyo, JP;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 48/00 (2006.01); C07H 21/02 (2006.01); C07H 21/04 (2006.01); C12N 15/11 (2006.01); C12N 15/113 (2010.01); C12Q 1/68 (2006.01);
U.S. Cl.
CPC ...
C12N 15/113 (2013.01); C12Q 1/6876 (2013.01); C12N 2310/11 (2013.01); C12N 2310/3233 (2013.01); C12N 2320/10 (2013.01); C12N 2320/33 (2013.01); C12N 2330/30 (2013.01); C12Q 2600/136 (2013.01); C12Q 2600/178 (2013.01);
Abstract
Provided is a drug that allows highly-efficient skipping of exon. The present invention provides an antisense oligomer wherein two or more unit oligomers targeting sequences that are neither consecutive nor overlap with each other in the same exon are connected.