The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 12, 2017
Filed:
Jul. 30, 2013
National University Corporation Nagoya University, Nagoya-shi, Aichi, JP;
Medical & Biological Laboratories Co., Ltd., Nagoya-shi, Aichi, JP;
Kenji Kadomatsu, Nagoya, JP;
Satoshi Kishida, Nagoya, JP;
Kenichiro Ono, Nagoya, JP;
Kasumi Yagi, Aichi, JP;
NATIONAL UNIVERSITY CORPORATION NAGOYA UNIVERSITY, Nagoya-shi, JP;
MEDICAL & BIOLOGICAL LABORATORIES CO., LTD., Nagoya-shi, JP;
Abstract
A monoclonal antibody, which recognizes at least two amino acids among amino acids located at position 69, position 79, position 81 and position 102 of human midkine, has been found to have excellent reactivity with and excellent neutralizing activity against human midkine. Moreover, the activity of suppressing the proliferation of tumor has been observed in the antibody having excellent neutralizing activity. The use of the antibody of the present invention makes it possible to treat cancer effectively and to detect or purify midkine efficiently.