The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 12, 2017

Filed:

Apr. 03, 2008
Applicants:

Weidong Zhou, Fujian, CN;

Xiaojin Liao, Fujian, CN;

LI Sun, Fujian, CN;

Linzhong Zhang, Fujian, CN;

Qingsong LU, Fujian, CN;

Shiye Shen, Fujian, CN;

Lishan Yang, Fujian, CN;

Defang Zhang, Fujian, CN;

Huihuang Lin, Fujian, CN;

Ping Zhang, Fujian, CN;

Inventors:

Weidong Zhou, Fujian, CN;

Xiaojin Liao, Fujian, CN;

Li Sun, Fujian, CN;

Linzhong Zhang, Fujian, CN;

Qingsong Lu, Fujian, CN;

Shiye Shen, Fujian, CN;

Lishan Yang, Fujian, CN;

Defang Zhang, Fujian, CN;

Huihuang Lin, Fujian, CN;

Ping Zhang, Fujian, CN;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 38/27 (2006.01); C07K 14/00 (2006.01); C07K 14/61 (2006.01); A61K 47/60 (2017.01);
U.S. Cl.
CPC ...
C07K 14/61 (2013.01); A61K 38/27 (2013.01); A61K 47/60 (2017.08);
Abstract

The growth hormone with high biological activity modified by the double-stranded polyethylene glycol at a single site and the preparation method thereof are provided. The PEGylated growth hormone has a higher biological activity and a longer half-life than the unmodified growth hormone. The composition comprising the PEGylated growth hormone is useful in the treatment of the growth or development disorder such as growth hormone deficiency, Turner syndrome etc.


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