The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 12, 2017
Filed:
Apr. 29, 2014
Memorial Sloan Kettering Cancer Center, New York, NY (US);
The Rockefeller University, New York, NY (US);
Rutgers, the State University of New Jersey, New Brunswick, NJ (US);
University of Bonn, Bonn, DE;
Dinshaw Patel, New York, NY (US);
Thomas Tuschl, New York, NY (US);
Manuel Ascano, Jr., New York, NY (US);
Yang Wu, New York, NY (US);
Yizhou Liu, New York, NY (US);
Winfried Barchet, Bonn, DE;
Gunther Hartmann, Bonn, DE;
Thomas Zillinger, Bonn, DE;
Roger Jones, Martinsville, NJ (US);
Barbara L. Gaffney, Hillsborough, NJ (US);
Pu Gao, New York, NY (US);
Memorial Sloan Kettering Cancer Center, New York, NY (US);
Rutgers, The State University of New Jersey, New Brunswick, NJ (US);
The Rockefeller University, New York, NY (US);
University of Bonn, Bonn, DE;
Abstract
The present disclosure provides, among other things, novel cyclic-GMP-AMP (cGAMP) analogs, mimics, mimetics and variants, and compositions and kits thereof; methods of using the compounds as described herein for treating cancer, and immune disease, disorders, or conditions; methods of using the compounds as described herein for modulating cGAS and STING; and methods of designing or characterizing a cGAS modulator.