The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 12, 2017

Filed:

Jul. 24, 2014
Applicants:

Novartis Ag, Basel, CH;

Zhenxing Du, Shanghai, CN;

Samuel Hintermann, Basel, CH;

Konstanze Hurth, Lorrach, DE;

Sebastien Jacquier, Hegenheim, FR;

Hansjoerg Lehmann, Basel, CH;

Henrik Moebitz, Freiburg, DE;

Nicolas Soldermann, Village-Neuf, FR;

Aleksandar Stojanovic, Basel, CH;

Inventors:

Zhenxing Du, Shanghai, CN;

Samuel Hintermann, Basel, CH;

Konstanze Hurth, Lorrach, DE;

Sébastien Jacquier, Hegenheim, FR;

Hansjoerg Lehmann, Basel, CH;

Henrik Moebitz, Freiburg, DE;

Nicolas Soldermann, Village-Neuf, FR;

Aleksandar Stojanovic, Basel, CH;

Assignee:

Novartis AG, Basel, CH;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 403/14 (2006.01); C07D 401/14 (2006.01); C07D 417/14 (2006.01); C07D 473/16 (2006.01); A61K 31/517 (2006.01); A61K 31/52 (2006.01);
U.S. Cl.
CPC ...
C07D 403/14 (2013.01); A61K 31/517 (2013.01); A61K 31/52 (2013.01); C07D 401/14 (2013.01); C07D 417/14 (2013.01); C07D 473/16 (2013.01);
Abstract

Provided are substituted quinazolin-4-one compounds of the formula (I) and/or pharmaceutically acceptable salts and/or solvates thereof, wherein R, R, R, R, Rand L are as defined in the description. Such compounds are suitable for the treatment of a disorder or disease which is mediated by the activity of the class I PI3K kinases.


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