The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 12, 2017
Filed:
Jun. 06, 2016
Applicant:
Cb Therapeutics Inc., Grand Cayman, KY;
Inventor:
Deyi Zhang, Beijing, CN;
Assignee:
CB THERAPEUTICS INC., Grand Cayman, KY;
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07D 403/12 (2006.01); C07D 239/47 (2006.01); A61K 31/44 (2006.01); A61K 31/4427 (2006.01); A61K 31/505 (2006.01); A61K 31/506 (2006.01); C07D 213/75 (2006.01); C07D 401/12 (2006.01); C07D 413/12 (2006.01); C07D 213/68 (2006.01); C07D 213/72 (2006.01); C07D 405/12 (2006.01);
U.S. Cl.
CPC ...
C07D 239/47 (2013.01); A61K 31/44 (2013.01); A61K 31/4427 (2013.01); A61K 31/505 (2013.01); A61K 31/506 (2013.01); C07D 213/68 (2013.01); C07D 213/72 (2013.01); C07D 213/75 (2013.01); C07D 401/12 (2013.01); C07D 403/12 (2013.01); C07D 405/12 (2013.01); C07D 413/12 (2013.01);
Abstract
The present disclosure relates to novel cyclopropanecarboxamido-substituted aromatic compounds that inhibit protein kinases and their use in anti-tumor area. In particular, the disclosure relates to novel tyrosine-kinase inhibitors and Raf-kinase inhibitors as anti-tumor agents, their preparation, pharmaceutical composition, and their use in the treatment of cancer.