The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 12, 2017

Filed:

Oct. 24, 2014
Applicant:

Neuroplast Beheer B.v., Maastricht, NL;

Inventors:
Assignee:

NEUROPLAST BEHEER B.V., Maastricht, NL;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 35/12 (2015.01); A61K 35/28 (2015.01); A01K 67/027 (2006.01); A61K 35/16 (2015.01); C12N 5/00 (2006.01); C12N 5/0789 (2010.01); C12N 5/0775 (2010.01); A61K 38/17 (2006.01);
U.S. Cl.
CPC ...
A61K 35/28 (2013.01); A01K 67/0271 (2013.01); A61K 35/16 (2013.01); A61K 38/1722 (2013.01); C12N 5/0087 (2013.01); C12N 5/0647 (2013.01); C12N 5/0663 (2013.01); A01K 2207/30 (2013.01); A01K 2227/105 (2013.01); A01K 2267/0356 (2013.01); A01K 2267/0368 (2013.01); A61K 2035/124 (2013.01); C12N 2533/56 (2013.01);
Abstract

The disclosure is in the field of cell therapy, more in particular, stem cell transplantation therapy. The disclosure provides methods and compositions for improving the efficacy of stem cell transplantation therapy by reducing the inflammatory activity of a stem cell transplant. More in particular, the disclosure provides a method for preparing a stem cell transplant with reduced inflammatory activity comprising a step of suspending a composition comprising stem cells in a fibrinogen-depleted plasma and/or in a fibrinogen and C-reactive protein-depleted plasma.


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