The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 05, 2017

Filed:

Sep. 08, 2014
Applicant:

Affinity Biosensors, Llc, Santa Barbara, CA (US);

Inventors:

Ken Babcock, Santa Barbara, CA (US);

Cynthia Schneider, Santa Barbara, CA (US);

Assignee:

Affinity Biosensors, LLC, Santa Barbara, CA (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12Q 1/02 (2006.01); C12Q 1/28 (2006.01); C12M 1/34 (2006.01); G01N 33/50 (2006.01); C12Q 1/18 (2006.01); G01N 15/10 (2006.01); G01N 33/543 (2006.01); G01N 27/447 (2006.01);
U.S. Cl.
CPC ...
G01N 33/5011 (2013.01); C12Q 1/18 (2013.01); G01N 15/10 (2013.01); G01N 27/447 (2013.01); G01N 33/54373 (2013.01); G01N 2015/1006 (2013.01); G01N 2015/1043 (2013.01); G01N 2500/04 (2013.01);
Abstract

System and Method for measuring the growth of a bacterial culture and its response to one or more antimicrobials using measurement of mass of individual microbes. Methods include periodic sampling, determining change in mass and concentration, and comparing growth rates of cultures in nutrient broth vs. mixtures containing various antibiotic mixtures. A number of antimicrobials can be compared in one measurement by multiplexing or using multiple sensors to measure in parallel. Growth and antibiotic efficacy can be assessed at low concentrations at the onset of growth, typically within 1 to 2 hours.


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