The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 05, 2017

Filed:

Jul. 15, 2011
Applicants:

Michael J. Taylor, Mt. Pleasant, SC (US);

Simona C. Baicu, Charleston, SC (US);

David Kravitz, Barrington Hills, IL (US);

Inventors:

Michael J. Taylor, Mt. Pleasant, SC (US);

Simona C. Baicu, Charleston, SC (US);

David Kravitz, Barrington Hills, IL (US);

Assignee:

LIFELINE SCIENTIFIC, INC., Itasca, IL (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12N 5/071 (2010.01); A01N 1/02 (2006.01);
U.S. Cl.
CPC ...
C12N 5/0676 (2013.01); A01N 1/0247 (2013.01);
Abstract

Methods of isolating cellular products, such as pancreatic islets, may be used in diabetes research and therapeutic transplantation. The methods may involve providing a donor tissue having desired cells and undesired cells, perfusing the donor tissue with a perfusion solution, developing edema during perfusion of the donor tissue to form a swelled tissue, and separating the desired cells from undesired cellular material to obtain a cellular product. The methods may also include disrupting the tissue, and separating the desired cells from undesired cellular material to obtain the cellular product. The methods may result in an increased yield of cellular product that retains sufficient functional integrity to be useful as a transplantation resource.


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