The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 05, 2017
Filed:
Nov. 21, 2012
University Health Network, Toronto, CA;
Sunnybrook Research Institute, Toronto, CA;
Gordon Keller, Toronto, CA;
Juan Carlos Zuniga-Pflucker, Toronto, CA;
Marion J. Kennedy, Toronto, CA;
Christopher Michael Sturgeon, Toronto, CA;
Andrea Ditadi, Toronto, CA;
Geneve Sheandra Awong, Toronto, CA;
UNIVERSITY HEALTH NETWORK, Toronto, CA;
SUNNYBROOK RESEARCH INSTITUTE, Toronto, CA;
Abstract
There is described herein a method of enriching a population of stem cells for hematopoietic progenitors. The method comprises inducing hematopoietic differentiation in a population of human embryonic stem cells or human induced pluripotent stem cells; sorting the population based on expression of CD43 and at least one of CD34, CD31 and CD144; and selecting a fraction that is at least one of CD34+CD43−, CD31+CD43− and CD144+CD43−. Also provided are populations of hematopoietic progenitors obtained by the methods described herein.