The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 05, 2017
Filed:
Dec. 18, 2012
Mogam Biotechnology Institute, Gyeonggi-do, KR;
Green Cross Labcell, Gyeonggi-do, KR;
Bokyung Min, Gyeonggi-do, KR;
Hana Choi, Gyeonggi-do, KR;
Okjae Lim, Gyeonggi-do, KR;
Jung Hyun Her, Gyeonggi-do, KR;
Sangmi Kang, Gyeonggi-do, KR;
Eun-Kyoung Lee, Gyeonggi-do, KR;
Hyejin Chung, Gyeonggi-do, KR;
Yu Kyeong Hwang, Gyeonggi-do, KR;
GREEN CROSS LABCELL, Gyeonggi-Do, KR;
MOGAM BIOTECHNOLOGY INSTITUTE, Gyeonggi-Do, KR;
Abstract
The present invention relates to a method for producing natural killer cells (hereinafter, referred to as 'NK cells'), NK cells produced thereby, and a composition for treating cancers and infectious diseases containing the same. The present invention provides a method for producing NK cells, which maintain high cytotoxicity and cell viability to exhibit high therapeutic effects against cancers and infectious diseases and can be cultured ex vivo at high efficiency and high concentration. In addition, a culture method which maintains cell concentration at a constant level is used for the production of NK cells, and thus the overgrowth of the cells can be prevented so that the cells can be maintained at an optimal state. Particularly, even when the cells are thawed after freezing, the function of the cells is not impaired, and the NK cells can maintain high cell viability and cytotoxicity. Thus, the NK cells can be easily stored and supplied in a liquid or frozen state without needing an additional treatment process.