The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 05, 2017
Filed:
Dec. 17, 2014
Merck Sharp & Dohme Corp., Rahway, NJ (US);
William K. Hagmann, Westfield, NJ (US);
Bing Li, Towaco, NJ (US);
Jason W. Szewczyk, Collegeville, PA (US);
Bowei Wang, Westfield, NJ (US);
Dann Parker, Cranford, NJ (US);
Timothy Blizzard, Princeton, NJ (US);
Hubert Josien, Jersey City, NJ (US);
Purakkattle Biju, Westwood, MA (US);
Harry Chobanian, Aberdeen, NJ (US);
Candido Gude, Staten Island, NY (US);
Ravi P. Nargund, East Brunswick, NJ (US);
Barbara Pio, West Orange, NJ (US);
Qun Dang, Westfield, NJ (US);
Linus S. Lin, Shanghai, CN;
Bin Hu, Shanghai, CN;
Mingxiang Cui, Shanghai, CN;
Zhengxia Chen, Shanghai, CN;
Meibi Dai, Shanghai, CN;
Zaihong Zhang, Shanghai, CN;
Ying Lv, Shanghai, CN;
Lili Tian, Shanghai, CN;
Merck Sharp & Dohme Corp., Rahway, NJ (US);
Abstract
The present invention relates to a compound represented by formula (I): and pharmaceutically acceptable salts thereof. The compounds of formula I are agonists of G-protein coupled receptor 40 (GPR40) and may be useful in the treatment, prevention and suppression of diseases mediated by the G-protein-coupled receptor 40. The compounds of the present invention may be useful in the treatment of Type 2 diabetes mellitus, and of conditions that are often associated with this disease, including obesity and lipid disorders, such as mixed or diabetic dyslipidemia, hyperlipidemia, hypercholesterolemia, and hypertriglyceridemia.