The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 05, 2017

Filed:

Nov. 20, 2015
Applicants:

Tianjin University, Tianjin, CN;

Hainan Lingkang Pharmaceutical Co., Ltd, Haikou, CN;

Inventors:

Ying Bao, Tianjin, CN;

Linggang Tao, Haikou, CN;

Long Li, Tianjin, CN;

Hongxun Hao, Tianjin, CN;

Jun Lv, Haikou, CN;

Baohong Hou, Tianjin, CN;

Assignees:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 401/12 (2006.01);
U.S. Cl.
CPC ...
C07D 401/12 (2013.01); C07B 2200/13 (2013.01);
Abstract

It discloses Omeprazole Sodium semihydrate and preparation method thereof, wherein every mole of Omeprazole Sodium semihydrate contains 0.5 mole of water, and it has an X-ray diffraction pattern comprising characteristic peaks at diffraction angles 2θ of 6.26°±0.1°, 11.10°±0.1°, 12.20°±0.1°, 15.58°±0.1°, 16.02°±0.1°, 17.12°±0.1°, 19.08°±0.1°, 21.00°±0.1°, 22.68°±0.1°, 23.48°±0.1°, 24.08°±0.1°, 26.52°±0.1° and 28.08°±0.1°. A raw material of Omeprazole Sodium hydrate is added into an organic solvent, stirring for 2˜9 hours at constant temperature of 25˜60° C., thereafter Omeprazole Sodium semihydrate is provided after filtrating and drying.


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