The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 05, 2017
Filed:
Jun. 01, 2016
Jenkem Technology Co., Ltd. (Beijing), Haidan District, Beijing, CN;
Zewang Feng, Beijing, CN;
Jianhuan Jia, Beijing, CN;
Yan Liu, Beijing, CN;
Zhenguo Wang, Beijing, CN;
Xuan Zhao, Beijing, CN;
Jenkem Technology Co., Ltd. (Beijing), Beijing, CN;
Abstract
Disclosed are a 3-furyl-2-cyano-2-acrylamide derivative with epidermal growth factor receptor (EGFR) inhibitory activity and pharmaceutical acceptable salt thereof, together with preparation method thereof, pharmaceutical composition comprising the compound, and application of the compound in treating senile dementia (AD). The new compound is shown as formula I, wherein Ris selected from the group consisting of H, C-Calkyl, C-Calkenyl, C-Calkynyl and C-Ccycloalkyl; Ris selected from the group consisting of alkyl, cycloalkyl, alkenyl, alkynyl, aryl, heteroaryl, aralkyl and heteroaralkyl; X is selected from the group consisting of CH, NH, O and S; m and n are all integers greater than or equal to zero.