The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 05, 2017
Filed:
Jun. 05, 2014
Applicant:
Sanofi, Paris, FR;
Inventors:
Andreas Evers, Frankfurt am Main, DE;
Christopher Kallus, Frankfurt am Main, DE;
Michael Wagner, Frankfurt am Main, DE;
Hermut Wehlan, Frankfurt am Main, DE;
Assignee:
SANOFI, Paris, FR;
Primary Examiner:
Int. Cl.
CPC ...
C07D 413/12 (2006.01); C07D 273/01 (2006.01); A61K 31/395 (2006.01); A61K 31/4427 (2006.01); A61P 7/02 (2006.01); A61K 45/06 (2006.01); C07D 213/75 (2006.01);
U.S. Cl.
CPC ...
C07D 273/01 (2013.01); A61K 31/395 (2013.01); A61K 31/4427 (2013.01); A61K 45/06 (2013.01); C07D 213/75 (2013.01); C07D 413/12 (2013.01);
Abstract
The present invention relates to macrocydic urea derivatives of the formula I (I) in which R1, R2, R3, V and Y are as defined below. The compounds of the formula I are inhibitors of the enzyme TAFIa (activated thrombin-activatable fibrinolysis inhibitor). The invention further relates to the process for the preparation of the compounds of formula I and to the use thereof as medicaments.