The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 05, 2017
Filed:
Jul. 25, 2013
Hanmi Pharm. Co., Ltd., Hwaseong-si, Gyeonggi-do, KR;
Hyung Kyu Lim, Hwaseong-si, KR;
Hyun Uk Kim, Busan, KR;
Mi Kyoung Lee, Seoul, KR;
Jong Soo Lee, Seongnam-si, KR;
Sung Min Bae, Seongnam-si, KR;
Se Chang Kwon, Seoul, KR;
HANMI PHARM. CO., LTD, Hwaseong-Si, KR;
Abstract
The present invention relates to a liquid formulation of a combination of long-acting insulin and insulinotropic peptide, comprising insulin which is a physiologically active peptide, insulinotropic peptide, and albumin-free stabilizer, wherein the stabilizer comprises a buffer, a sugar alcohol, a non-ionic surfactant, and an isotonic agent; and a method for preparing the liquid formulation. The liquid formulation of the present invention does not contain a human serum albumin and potentially toxic factors to the body, and thus it has excellent storage stability for insulin conjugate and insulinotropic peptide conjugate at high concentration, without a risk of viral contamination.