The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 9833480 B1

PDF
Full Text
Expired
Date of Patent:
Dec. 05, 2017

Filed:

Apr. 14, 2011
Applicants:

Richard P. Junghans, Boston, MA (US);

Nithianandan Selliah, Providence, RI (US);

Inventors:

Richard P. Junghans, Boston, MA (US);

Nithianandan Selliah, Providence, RI (US);

Assignee:

Prospect Chartercare, LLC, Providence, RI (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 14/705 (2006.01); A61K 35/30 (2015.01); C07K 14/73 (2006.01); A61K 48/00 (2006.01); A61K 38/17 (2006.01);
U.S. Cl.
CPC ...
A61K 35/30 (2013.01); C07K 14/70514 (2013.01); A61K 38/1774 (2013.01); A61K 48/00 (2013.01); C07K 2319/03 (2013.01); C07K 2319/33 (2013.01); C07K 2319/735 (2013.01); C07K 2319/74 (2013.01); C07K 2319/90 (2013.01); C12N 2799/027 (2013.01);
Abstract

The invention features nucleic acid constructs encoding chimeric immune T-cell receptors (CIRs) that are useful for treating HIV in patients. In general, the CIRs contain an extracellular domain which targets HIV or HIV infected cells (e.g., the extracellular domain of CD4), a transmembrane domain, and a cytoplasmic domain for mediating T-cell activation (e.g., CD3 zeta and/or the partial extracellular domain of CD28). The invention also features the use of host cells expressing CIRs in the treatment of HIV.


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Junghans, Richard. (2017). Methods and compositions for treating hiv (U.S. Patent No. 9833480). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/9833480

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