The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 05, 2017

Filed:

Dec. 16, 2015
Applicant:

Arthrex, Inc., Naples, FL (US);

Inventors:

Christopher M. Bare, Naples, FL (US);

Brandon L. Roller, Naples, FL (US);

Melissa S. Tucker, Bonita Springs, FL (US);

Assignee:

ARTHREX, INC., Naples, FL (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 38/00 (2006.01); A61K 35/16 (2015.01); A61K 38/17 (2006.01); A61M 1/36 (2006.01); C07K 16/24 (2006.01); A61J 1/20 (2006.01);
U.S. Cl.
CPC ...
A61K 35/16 (2013.01); A61K 38/1793 (2013.01); A61M 1/362 (2014.02); C07K 16/245 (2013.01); A61J 1/2089 (2013.01);
Abstract

Techniques and devices for removing (filtering out) unwanted/inhibitory components (for example, products, byproducts and/or cell output such as inhibitory catabolic proteins) from a composition (for example, autologous fluid or serum) containing such unwanted/inhibitory components. The devices include at least one construct designed to contain a composition (for example, autologous fluid or serum) containing inhibitory/unwanted components (products, byproducts and/or output of cells such as inhibitory catabolic proteins). The construct is provided with interior walls including specific protein capturing means designed to remove the inhibitory/unwanted component(s) (for example, specific protein(s)) from the composition. Proteins targeted for capture include, but are not limited to, catabolic cytokines such as IL-1β, IL-α, IL-6, TNFα, IFNγ and MMPS as these proteins inhibit the healing process.


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