The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 05, 2017
Filed:
Apr. 01, 2015
Applicant:
Bristol-myers Squibb Company, Princeton, NJ (US);
Inventors:
Kenneth M. Boy, Durham, CT (US);
Stephen E. Mercer, Middletown, CT (US);
Richard E. Olson, Orange, CT (US);
Xiaoliang Zhou, Guilford, CT (US);
Assignee:
Bristol-Myers Squibb Company, Princeton, NJ (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 239/70 (2006.01); C07D 491/00 (2006.01); C07D 471/00 (2006.01); C07D 413/00 (2006.01); A61K 31/517 (2006.01); C07D 403/12 (2006.01);
U.S. Cl.
CPC ...
A61K 31/517 (2013.01); C07D 403/12 (2013.01); A61K 2121/00 (2013.01);
Abstract
The compound N2-(3-(difluoromethoxy)-4-(3-methyl-1H-1,2,4-triazol-1-yl)phenyl)-7-(4-fluorophenyl)-N4,5,5-trimethyl-6,7-dihydro-5H-cyclopenta[d]pyrimidine-2,4-diamine: [PLEASE INSERT CHEMICAL STRUCTURE HERE] reduces -amyloid peptide (A 42) production and has low potential for bioactivation, and may be useful in the treatment of Alzheimer's Disease and other conditions affected by -amyloid peptide (A 42) production.