The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 05, 2017

Filed:

Nov. 20, 2014
Applicant:

Hanmi Pharm. Co., Ltd., Hwaseong-si, Gyeonggi-do, KR;

Inventors:

Ho Taek Im, Yongin-si, KR;

Myoung Ki Jeong, Suwon-si, KR;

Yong Il Kim, Suwon-si, KR;

Jae Hyun Park, Suwon-si, KR;

Jong Soo Woo, Suwon-si, KR;

Hyuk Jun Cho, Suwon-si, KR;

Assignee:

HANMI PHARM. CO., LTD, Hwaseong-si, KR;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 9/24 (2006.01); A61K 31/505 (2006.01); A61K 31/4422 (2006.01); A61K 31/4178 (2006.01); A61K 9/20 (2006.01);
U.S. Cl.
CPC ...
A61K 9/209 (2013.01); A61K 31/4178 (2013.01); A61K 31/4422 (2013.01); A61K 31/505 (2013.01); A61K 9/2018 (2013.01); A61K 9/2054 (2013.01); A61K 9/2095 (2013.01);
Abstract

Disclosed is a pharmaceutical combination formulation comprising a first discrete part containing amlodipine and rosuvastatin and a second discrete part containing losartan, which exhibits improved dissolution rate and stability. The inventive combination formulation comprising amlodipine, losartan and rosuvastatin having different action mechanisms from one another can be effectively used to prevent or treat a cardiovascular disorder. Designed to minimize an interaction among active ingredients, the pharmaceutical combination formulation exhibits excellent storage stability and dissolution rates of amlodipine, losartan and rosuvastatin, and thus can be useful in pharmaceutical industries.


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