The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 05, 2017
Filed:
Oct. 31, 2013
Amgen Research (Munich) Gmbh, Munich, DE;
Takeda Gmbh, Constance, DE;
Markus Rast, Radolfzell, DE;
Wolfram Steinhilber, Stockach, DE;
Christian de Muynck, Constance, DE;
Gerhard Becker, Allensbach, DE;
Pernille Dybendal Pedersen, Frederiksberg, DK;
Thomas Urbig, Munich, DE;
Thomas Boehm, Munich, DE;
Takeda GmbH, Constance, DE;
Amgen Research (Munich) GmbH, Munich, DE;
Abstract
The present invention relates to aqueous formulations comprising at least 20 mg/ml of a compound neutralizing GM-CSF, a lyoprotectant and an amino acid and/or a buffer. The ingredients of the formulation preferably provide stability to the compound neutralizing GM-CSF in view of lyophilization, storage and reconstruction. In a preferred aspect, the formulation, e.g. after reconstruction, is for use in therapy, preferably for use in the treatment of inflammatory and autoimmune disorders, preferably including allergic and psoriatic disorders, as well as arthritic and asthmatic disorders. Furthermore, a kit comprising the formulation of the invention is provided.