The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 28, 2017
Filed:
Dec. 01, 2005
Applicants:
Andreas Bergmann, Berlin, DE;
Joachim Struck, Berlin, DE;
Nils G. Morgenthaler, Berlin, DE;
Inventors:
Assignee:
ADRENOMED AG, Hennigsdorf, DE;
Primary Examiner:
Int. Cl.
CPC ...
G01N 33/53 (2006.01); A61K 39/395 (2006.01); G01N 33/74 (2006.01); C07K 16/26 (2006.01);
U.S. Cl.
CPC ...
G01N 33/74 (2013.01); A61K 39/3955 (2013.01); C07K 16/26 (2013.01);
Abstract
The ratio of concentrations of pro-adrenomedullin (pro-ADM)/pro-endothelin (pro-END) immunoreactivity in body fluids of critically ill patients is used as for the diagnosis, course control and prognosis, including an assessment of the mortality risk, of severe life threatening diseases. Further, a treatment of critically ill patients having high levels of pro-ADM but insufficient levels of pro-END immunoreactivities with a medicament comprising vasoconstrictive endothelin or its precursors, and/or endothelin agonists or adrenomedullin antagonists is provided.