The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 28, 2017

Filed:

Jun. 17, 2014
Applicant:

Waters Technologies Corporation, Milford, MA (US);

Inventors:

Geoff C. Gerhardt, Woonsocket, RI (US);

Martin Gilar, Franklin, MA (US);

Bernard Bunner, Newton, MA (US);

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01N 30/20 (2006.01); G01N 30/86 (2006.01); G01N 30/60 (2006.01); G01N 30/02 (2006.01);
U.S. Cl.
CPC ...
G01N 30/8668 (2013.01); G01N 30/8665 (2013.01); G01N 30/6095 (2013.01); G01N 2030/027 (2013.01);
Abstract

Provided are systems and methods for adapting to volume variations in microfluidic chromatography columns. A column is calibrated by comparing a parameter of the column with a same parameter of a reference column and generating, by a processor, an adjustment factor in response to the comparison between the parameter of the column with a same parameter of the reference column. Volume differences between the calibrated column and the reference column are compensated for by integrating the generated adjustment factor into a sample separation involving the calibrated column.


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