The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 28, 2017

Filed:

Mar. 29, 2012
Applicants:

Meng LU, Champaign, IL (US);

Chun GE, Urbana, IL (US);

Brian T. Cunningham, Champaign, IL (US);

Stephen Schulz, Lee, NH (US);

Inventors:

Meng Lu, Champaign, IL (US);

Chun Ge, Urbana, IL (US);

Brian T. Cunningham, Champaign, IL (US);

Stephen Schulz, Lee, NH (US);

Assignees:
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
G01N 21/64 (2006.01); H01S 3/1055 (2006.01); H01S 5/14 (2006.01);
U.S. Cl.
CPC ...
G01N 21/6428 (2013.01); G01N 21/6458 (2013.01); G01N 2021/6421 (2013.01); H01S 3/1055 (2013.01); H01S 5/141 (2013.01); H01S 5/142 (2013.01);
Abstract

A label-free biosensor detection arrangement incorporating an external cavity laser (ECL) includes a tunable lasing element (e.g. an antireflection coated laser diode or semiconductor optical amplifier) and a narrow bandwidth resonant reflectance filter as the wavelength-selective element for the tunable lasing element. A sample is deposited on the surface of the resonant reflectance filter containing a biological material. The wavelength emitted by the external cavity laser is continuously tunable by binding interactions between the biological material and the resonant reflectance filter or adsorption of the biological material present in the sample on resonant reflectance filter. The narrow bandwidth resonance reflectance filter can take the form of photonic crystal (PC), a Bragg stack, or a Brag fiber reflection filter.


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