The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 28, 2017

Filed:

Feb. 19, 2016
Applicant:

Seoul National University R&db Foundation, Seoul, KR;

Inventors:

In ah Kim, Seongnam-si, KR;

Dan Hyo Kim, Goseong-gun, KR;

Jean ny Kwon, Seoul, KR;

Ji Min Park, Yongin-si, KR;

Young hee Park, Seoul, KR;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/4709 (2006.01); C12N 15/113 (2010.01); C07H 21/02 (2006.01);
U.S. Cl.
CPC ...
C12N 15/1137 (2013.01); A61K 31/4709 (2013.01); C12N 2310/14 (2013.01); C12N 2320/31 (2013.01);
Abstract

The present disclosure relates to a composition for enhancing radiation sensitivity including a PI4K isozyme inhibitor as an active ingredient. As the PI4K isozyme inhibitor, a PI4K isozyme-specific siRNA or antiviral agent according to the present disclosure has an excellent effect of enhancing radiation sensitivity such as reducing viability of the cancer cells and radiation resistance during in radiation irradiation and suppressing and delaying DNA damage repair induced by the radiation by inhibiting the PI4K isozyme to be used as a radiation sensitivity adjuvant and an anticancer treatment assisting agent.


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