The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 28, 2017
Filed:
Aug. 13, 2013
Applicant:
Cedars-sinai Medical Center, Los Angeles, CA (US);
Inventors:
Eduardo Marban, Los Angeles, CA (US);
Ke Cheng, Los Angeles, CA (US);
Ahmed Ibrahim, Los Angeles, CA (US);
Assignee:
CEDARS SINAI MEDICAL CENTER, Los Angeles, CA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 15/113 (2010.01); C12N 15/11 (2006.01); A61K 31/7105 (2006.01); A61K 35/34 (2015.01); A61K 47/46 (2006.01); C12N 5/077 (2010.01); A61K 9/00 (2006.01); A61K 47/42 (2017.01);
U.S. Cl.
CPC ...
C12N 15/113 (2013.01); A61K 31/7105 (2013.01); A61K 35/34 (2013.01); A61K 47/46 (2013.01); C12N 5/0657 (2013.01); C12N 15/111 (2013.01); A61K 9/0019 (2013.01); A61K 47/42 (2013.01); C12N 2310/141 (2013.01); C12N 2320/30 (2013.01); C12N 2502/1329 (2013.01); C12N 2502/28 (2013.01);
Abstract
Several embodiments relate to methods of repairing and/or regenerating damaged or diseased tissue comprising administering to the damaged or diseased tissues compositions comprising exosomes. In several embodiments, the exosomes comprise one or more microRNA that result in alterations in gene or protein expression, which in turn result in improved cell or tissue viability and/or function.