The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 28, 2017
Filed:
Mar. 13, 2013
Applicants:
Sanbio, Inc., Mountain View, CA (US);
University of South Florida, Tampa, FL (US);
Inventors:
Cesar V. Borlongan, Tampa, FL (US);
Casey C. Case, San Mateo, CA (US);
Assignees:
SanBio, Inc., Mountain View, CA (US);
University of South Florida, Tampa, FL (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 35/28 (2015.01); A61K 9/00 (2006.01); C12N 9/64 (2006.01); C12N 5/079 (2010.01);
U.S. Cl.
CPC ...
C12N 9/6491 (2013.01); A61K 9/0085 (2013.01); A61K 35/28 (2013.01); C12N 5/0618 (2013.01); C12N 2501/42 (2013.01); C12N 2506/1353 (2013.01); C12N 2510/00 (2013.01); C12Y 304/24035 (2013.01);
Abstract
Disclosed herein are methods for the treatment of traumatic brain injury by transplantation of cells descended from marrow adherent stem cells that express an exogenous Notch intracellular domain. The transplanted cells form a pathway along which endogenous neurogenic cells proliferate and migrate from the subventricular zone to the site of injury.