The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 28, 2017

Filed:

Jun. 17, 2015
Applicant:

Millennium Pharmaceuticals, Inc., Cambridge, MA (US);

Inventor:

John Bertin, Winchester, MA (US);

Assignee:

Millennium Pharmaceuticals, Inc., Cambridge, MA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 16/00 (2006.01); C12N 9/12 (2006.01); C07K 14/47 (2006.01); C07K 16/40 (2006.01); C12N 15/113 (2010.01); C12Q 1/68 (2006.01); G01N 33/573 (2006.01); C07K 16/18 (2006.01); A61K 38/00 (2006.01);
U.S. Cl.
CPC ...
C12N 9/1229 (2013.01); C07K 14/4702 (2013.01); C07K 14/4747 (2013.01); C07K 16/18 (2013.01); C07K 16/40 (2013.01); C12N 15/1137 (2013.01); C12Q 1/6886 (2013.01); G01N 33/573 (2013.01); A61K 38/00 (2013.01); C07K 2317/76 (2013.01); C07K 2319/00 (2013.01); C12N 2310/11 (2013.01); C12N 2320/30 (2013.01); C12Q 2600/118 (2013.01); C12Q 2600/156 (2013.01); C12Q 2600/158 (2013.01);
Abstract

Novel CARD-9, CARD-10, or CARD-11 polypeptides, proteins, and nucleic acid molecules are disclosed. In addition to isolated CARD-9, CARD-10, or CARD-11 proteins, the invention further provides CARD-9, CARD-10, or CARD-11, fusion proteins, antigenic peptides and anti-CARD-9, CARD-10, or CARD-11 antibodies. The invention also provides CARD-9, CARD-10, or CARD-11 nucleic acid molecules, recombinant expression vectors containing a nucleic acid molecule of the invention, host cells into which the expression vectors have been introduced and non-human transgenic animals in which a CARD-9, CARD-10, or CARD-11 gene has been introduced or disrupted. Diagnostic, screening and therapeutic methods utilizing compositions of the invention are also provided.


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