The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 28, 2017

Filed:

Feb. 27, 2015
Applicant:

The Royal Institute for the Advancement of Learning / Mcgill University, Montreal, CA;

Inventors:

Michel L. Tremblay, Montreal, CA;

Claudia Penafuerte, Montreal, CA;

Matthew Feldhammer, Montreal, CA;

George Zogopoulos, Montreal, CA;

Cameron Black, Baie d'Urfe, CA;

Brian Kennedy, Kirkland, CA;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07F 9/6553 (2006.01); A61K 31/67 (2006.01); A61K 35/15 (2015.01); C12N 9/16 (2006.01); A61K 39/00 (2006.01); A61K 45/06 (2006.01);
U.S. Cl.
CPC ...
C07F 9/655354 (2013.01); A61K 31/67 (2013.01); A61K 35/15 (2013.01); A61K 39/0011 (2013.01); A61K 45/06 (2013.01); C12N 9/16 (2013.01); A61K 2039/5154 (2013.01);
Abstract

The invention encompasses the novel class of compounds represented by the Formula (I) below, which are inhibitors of the TC-PTP enzyme. The invention also encompasses pharmaceutical compositions which include the compounds shown above and methods of treating or preventing TC-PTP mediated diseases, including cancer, via their use in the activation of antigen-presenting cells, like dendritic cells, for applications in the immunotherapeutic treatment of diseases.


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