The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 28, 2017
Filed:
Nov. 13, 2013
Array Biopharma Inc., Boulder, CO (US);
Shelley Allen, Boulder, CO (US);
Steven Wade Andrews, Boulder, CO (US);
James F. Blake, Boulder, CO (US);
Barbara J. Brandhuber, Boulder, CO (US);
Kevin Ronald Condroski, San Diego, CA (US);
Julia Haas, Boulder, CO (US);
Yutong Jiang, Boulder, CO (US);
Timothy Kercher, San Diego, CA (US);
Gabrielle R. Kolakowski, Boulder, CO (US);
Shannon L. Winski, Boulder, CO (US);
Array BioPharma Inc., Boulder, CO (US);
Abstract
Compounds of Formula (I): or stereoisomers, tautomers, or pharmaceutically acceptable salts, or solvates or prodrugs thereof, where R, R, R, R, R, R, X, Ring B, and Ring C are as defined herein, and wherein Ring B moiety and the NH—C(═X)—NH moiety are in the trans configuration, are inhibitors of TrkA kinase and are useful in the treatment of diseases which can be treated with a TrkA kinase inhibitor such as pain, cancer, inflammation/inflammatory diseases, neurodegenerative diseases, certain infectious diseases, Sjogren's syndrome, endometriosis, diabetic peripheral neuropathy, prostatitis and pelvic pain syndrome.